Darren threw me a link to Humanized.com, a company who has a product called "Enso", which claims to deal with the fiddly little things that you are always having to do without getting in the way of your productivity.
It's a bit like quicksilver. You select something, hit a hotkey (capslock), type what you want to do (calculate, upper case, open, google, etc etc (not having to type everything of course)) and it does it. Looks like it's got a lot of potential as far as helping people work with their computers in a more logical way.... ie: you just tell it what you want to do (ie: upper case) instead of going to the right click -> properties -> characters -> upper case, or hitting a menu option, etc. Extensible with python (in the future) for doing potentially any interesting things.
They have two products currently, a launcher for $24.95 and a universal spellcheck and dictionary for $39.95.