Lifehacker has a good article on a subject dear to my heart, taming your cables and powercords. The Cordless workspace redux has some tips and equipment on how to get your desk area a bit cleaner. I'm using the wire tray myself, which works not badly, it at least moves the masses of cables up off the floor), though it's not 100%. I think I'll look for the long power strip this weekend and see if that makes things a bit easier.
Be sure to add the other article on the same subject.